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The therapeutic landscape is rapidly evolving

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Additionally, a chromosome aberration assay using human peripheral blood lymphocytes exposed to the extract at concentrations of 0.25, 0.5, 1, and 2 mg/ml and in vivo micronucleus test in mammalian erythrocyte cells that received doses of 500, 1,000, and 2,000 mg/kg also showed that the extract had no inhibitory effects on the mitotic index, the formation of micronuclei, or cell proliferation, and did not induce chromosomal abnormalities

den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ, Bakker BM