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Physiological pH and tonicity make it well-tolerated in rodent in vivo models

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Yes, and prevention is significantly more effective and less costly than correction

4 Discussion and conclusion Over the past decade, a substantial body of evidence has established the critical influence of gut-microbiota-derived metabolites, the composition of the gut microbiome, and dietary inputs on human health and disease states

doi: 10.1172/JCI30227 84 NeyensDZhaoHHustonNJWaymanGARitterRCAppleyardSM