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10.1073/pnas.0400181101 Proc

The therapeutic application of the PBN mechanism in MI/R involves three key strategies: (1) Targeted enzymatic therapy employing the Targ-CD39 fusion protein, which binds activated GPIIb/IIIa to enhance capillary density in infarcted myocardium while concurrently preventing thrombosis and vascular occlusion [45, 46, 48]

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