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Gastrointestinal Side Effects and Bleeding Risk Considerations One of the most common semaglutide side effects is gastrointestinal distress, reported in clinical trials by up to 25% of users in the first weeks of therapy

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If it impacts the testicular microenvironment, it could enhance sperm count or motility, but data are limited and the mechanism is different than how it might act in ovaries or endometrium

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10.1001/archinte.161.14.1733 18 CamilleriM.MayerE

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