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The blood-brain barrier in health and disease: important unanswered questions

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In this Review, we discuss the potential for single therapeutic agents, such as the xCT blocker sulfasalazine, the chloride regulator bumetanide, and the histone deacetylase inhibitor valproic acid, to manage both gliomas and associated epilepsy

Food and Drug Administration (FDA), and it is more likely with higher doses and after long-term use

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