However, in cases of chronic microbial dysbiosis induced by exposure to environmental toxicants, ingestion of a high-fat diet can cause changes in the GI environment that can enable distinct microbes to proliferate and infiltrate neighboring gut environments, and subsequently trigger deleterious inflammatory pathways (Figure 1) (Sun et al., 2018
Suicidal Ideation and Other Rare Undesirable Effects With the expanding role in diabetes and obesity, as well as potential extending therapeutic uses in the neurological area (e.g., stroke, neurodegenerative disorders, alcohol- and substance-use disorders), rare side effects have recently emerged
doi: 10.1007/s12325-019-00915-8 62 HansenBBNuhohoSAliSNDang-TanTValentineWJMalkinSJPet al
Stress is another known trigger that may push susceptible individuals into an autoimmune state
3 nmol/kg dose: PBS/PBS, n = 7
These results are in line with the previous work of Pocai et al