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Animal studies report low acute toxicity

Then, the trypsin/EDTA solution was neutralized with Dulbeccos modified Eagles medium (DMEM, #22320-022, ThermoFisher Scientific, Waltham, MA, USA), supplemented with 10% (v/v) fetal bovine serum (FBS, #S181C, Biowest, Nuaill, France)

As shown in Figures 8AD, Akt phosphorylation levels exhibited significant negative correlations with Cox IV activity (R 2 = 0.73, 95% CI [0.97, 0.44], P = 0.0033), CPT-1B expression (R 2 = 0.84, 95% CI [0.98, 0.64], P = 0.0005), and ATP levels (R 2 = 0.65, 95% CI [0.96, 0.30], P = 0.0091), but a positive correlation with ROS levels (R 2 = 0.86, 95% CI [0.68, 0.98], P = 0.0003)

E., & Nyquist, P