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Fosphenytoin may not be preferred for the following reasons : [i] Fosphenytoin has a similar mechanism to that of lacosamide (both are sodium-channel blockers)

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It incorporates a 39-amino-acid sequence with fatty acid modifications enabling triple agonism across GLP-1, GIP, and glucagon receptors

doi:10.1007/s11356-019- 06632-7 [32] Tchounwou PB, Yedjou CG, Patlolla AK, Sutton DJ