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Treatment with the ferroptosis inhibitor Ferrostatin-1 effectively alleviates high-glucose-induced macrophage injury and ferroptosis, reduces inflammatory responses in diabetic rat wounds, and improves angiogenesis, potentially via upregulating nuclear factor-E2-related factor 2 (Nrf2) expression [76]

Investigators also collected serial blood samples to track shifts in lipids, C-reactive protein, and liver enzymes, providing a broader picture of metabolic health

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Jan 2006;130(1):34-43

Sensitivity analyses for robust causal inference from mendelian randomization analyses with multiple genetic variants