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The in vitro hippocampal-neuron-culture spine-density work used Dihexa concentrations across a wide range, with effects observed at picomolar concentrations [2]

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10.1016/j.berh.2021.101723 [DOI] [PMC free article] [PubMed] [Google Scholar] 370.Qin, X

Hydrolysis of labile peptide bonds (especially Asp-Pro and Asn-Gly sequences common in many research peptides) accelerates