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However, scientific research shows that very high-dose oral B12 (1,000-2,000 mcg) can be effective for some, as about 1% can be absorbed without intrinsic factor

Th1 chemokines in autoimmune endocrine disorders

Nature Reviews Rheumatology 10: 593601

Nearly 4 in 10 adults (39%) are currently using, have used or are considering using these medications

CJC-1295, for example, is usually injected and can have effects that last for days, which if dosed incorrectly, poses the risk of sustaining hormone levels too long