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Semaglutide, a GLP-1 receptor agonist, and prednisone, a corticosteroid, differ significantly in their chemical structure, mechanism of action, therapeutic uses, and side effects

However, it also comes with certain potential risks

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Semaglutide also may cause thyroid C-cell tumors in rodents (with unknown risk shown in humans)

Some patients report urinary symptoms, but these do not establish direct causation and may relate to dehydration from gastrointestinal side effects