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Whether this model applies to MOR is important because some hypotheses propose that tolerance to morphine and other agonists that very weakly induce endocytosis is greater than to high-efficacy agonists such as DAMGO

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People with bleeding disorders or taking blood thinning medications should not take NAC because it may slow blood clotting ( NAC has an unpleasant smell that makes it hard to consume

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doi: 10.1007/s12035-013-8409-7

The more serious risks are rare but worth mentioning: infection at the injection site, fluid overload if the drip is administered too quickly, or allergic reactions to specific ingredients