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Reciprocal expression of IL-35 and IL-10 defines two distinct effector treg subsets that are required for maintenance of immune tolerance

Telehealth prescribing of GLP-1s is legal in all 50 states through licensed physicians

Ongoing Medical Supervision Every LeanMD patient receives regular physician check-ins, lab monitoring, and medication adjustments throughout all three phases of the program

As such, including an additional outcome with less clinically meaningful threshold would overload the study results with redundant information rather than providing added clinical insights

Further, some physicians have been somewhat hesitant to prescribe GLP-1s to patients due to coverage issues and other factors