By stimulating insulin secretion in response to elevated blood glucose levels, GLP-1 therapies help lower blood sugar levels
GLP-1 Therapy and Obesity Treatment Background The prevalence of obesity has markedly increased worldwide over the past decades
GSS, glutathione synthetase
Full safety profile Multiple species 96-well Service outputs aProximate TM Evaluation of KIM-1, NGAL, and clusterin, three FDA-approved biomarkers of kidney toxicity Cell viability: ATP, LDH, and TEER measurements Assays Kidney toxicity assays Assessment of renal drug safety Models aProximate TM kidney proximal tubule cells (from human, mouse, rat, and dog) Timeline 2-3 months How can Newcells kidney tissue models be used to assess renal toxicity
Unlike currently approved therapies such as semaglutide and tirzepatide, retatrutide acts on three metabolic pathways, leading many obesity medicine experts to view it as a potential next-generation treatment for obesity and related metabolic conditions
Ng, M., et al