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For tirzepatide (Mounjaro and Zepound), the percent weight loss in trials was larger, and varied by dosage (16% for 5mg, 22.5% for 15mg)

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Despite these choices, some patients with RRMS may not respond adequately to the initial therapy, necessitating a switch to alternative DMTs to better manage disease progression and activity

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DCI is especially important for insulin regulation, and research suggests that people with blood sugar dysregulation (as with PCOS) often have low levels of DCI

Future investigation using verified formulations and prospective clinical study designs is necessary to determine whether peptide-based therapies can be safely and meaningfully integrated into orthopedic care.