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Pfizer (NYSE:PFE) reported positive Phase 2b VESPER-3 data for its monthly injectable GLP-1 obesity therapy acquired from Metsera

Our study confirmed that the PI3K/Akt pathway acts downstream of GLP-1R in the TNC in CM mice

In the efficacy-estimand analysis, participants taking the highest dose (12 mg) lost an average of 28.7% of their body weight at 68 weeks, about 71.2 pounds from a baseline of 248.5 pounds

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Tang X, Wu H, Mao X, Li X, Wang Y (2020) The GLP-1 receptor herbal agonist morroniside attenuates neuropathic pain via spinal microglial expression of IL-10 and -endorphin

Semaglutide, generally, has shown greater efficacy in weight loss compared to Liraglutide in clinical trials