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Perhaps this administration method extends to the upper range of the estimated oral bioavailability (19-20%)

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Acta Pharmacol Toxicol 59(Suppl 7):450453 James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA (2004) Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism