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GLP-Rs structure allows for consistent receptor binding affinity and reliable results across a range of experimental models

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Studies have shown significant weight loss in individuals using these medications in conjunction with lifestyle changes

I notice in the marketing of these drugs that terms like sustained and long-term are being used to describe the weight loss, despite the fact that the studies these claims are based on offer a year and a half (or less!) of data, as if everyone involved got collective amnesia about the fact that past experience has shown that typically weight is regained in years 2-5