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BPC-157 demonstrates complex neurotransmitter system modulation[16]

What they found: Favorable safety profile , no serious adverse events at doses up to 100 g/kg Preliminary efficacy signals positive The program stopped before Phase 3 for unknown commercial reasons (the program passed through several sponsor rotations and no one ultimately carried it through) Why it matters: These are the only published clinical data in humans that we have

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SREBP-2 inhibition via siRNA lowered the expression of HMGCR , SQLE , LXR , CYP7A1 , and PCSK9 genes as well as HMGCR protein, and increased LDLR gene expression

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