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Pharmacological effects and mechanisms of Gastrodia elata and its active ingredients in the treatment of cardiovascular diseases

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Notoginsenoside Ft1 increases intracellular Ca accumulation, reduces 2+ cAMP levels by activating a signaling network mediated through P2Y receptors, and promotes platelet aggregation, thereby exerting a procoagulant effect

ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances (14)

Vials are stored in a monitored, temperature-controlled environment to maintain integrity prior to dispatch

M.DemeP.et al (2020b)