GLP-1s are the most successful, clinically-backed tools for diabetes and weight management on the planet, but side effects like nausea, diarrhea, constipation, fatigue, muscle loss are getting in the way
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These side effects were mild-to-moderate for most patients and decreased over time with continued exposure
p=0.0019)
Thank you to Robert Moskow, Managing Director and Senior Food & Beverage Analyst at Cowen Inc., Marc Washington, Founder of Supergut, Noah V., CEO & Co-Founder of Thrive Advisory Group, and Kevin Duffy, CEO of iFIT for leading today's discussion
In db/db mice, CK treatment increases secondary BAs, such as lithocholic acid (LCA) and deoxycholic acid (DCA) through changes in the gut microbiota, especially the Ruminococcaceae family, and up-regulation of cytochrome P450 family 7 subfamily B member 1 ( Cyp7b1 ) and cytochrome P450 family 27 subfamily A member 1 ( Cyp27a1 ) and down-regulation of cytochrome P450 family 8 subfamily B member 1 ( Cyp8b1 ), which changes BA biosynthesis from the classical pathway to the alternative pathway
