S.PeresL
Indeed, both CBS and CSE can synthesise cysteine persulphide (CysSSH) and poly-sulphides (CysS ( n ) SH) from cystine, 104,136 whereas 3-MP-activated 3-MST can generate from cysteine, glutathione or n -acetylcysteine, the corresponding per-sulphides (respectively, CysSSH, GSSH and NACSSH)
doi: 10.1172/JCI128521
Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]
Evert, A
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