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doi:10.1016/j.jad.2010.12.019, PMID: 21277635 Maes M, Van de Vyvere J, Vandoolaeghe E, Bril T, Demedts P, Wauters A, Neels H (1996) Alterations in iron metabolism and the erythron in major depression: further evidence for a chronic inflammatory process

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Consider: daily multivitamin, vitamin D 2,000-4,000 IU daily (most people are deficient), vitamin B12 if energy is low, calcium 1,000-1,200mg daily (especially for women), fiber supplement if constipated, protein powder if struggling to hit 80-100g daily from food

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Although lipid hydroperoxides can be detoxified by GPx4, the inhibition of cystine uptake and limitation of GSH synthesis impair this detoxification system, resulting in lipid peroxidation-dependent cell death (Fig

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While usually regarded as harmless, possible adverse effects include stomach pain

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10.2174/1874609811003020113 Curr

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