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PASC could encompass several adverse clinical impairments that may trigger chronic metabolic dysfunctions involving cardiovascular (CV), central/peripheral nervous (CNS/PNS), gastrointestinal (GI), pulmonary, reproductive, skeleto-muscular, and endocrinal systems 6,7

A pathway-level finding should not automatically be treated as a confirmed human outcome

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Although not an inclusion or exclusion criteria, use of SGLT2i was implemented to stratify patients as they were randomized in the trial

Most commercially significant generic challenges use Paragraph IV

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