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as photoreceptors contain abundant DHA levels, this suggests that the elevated retinal accumulation of lipid peroxidation is shuttled from the RPE into the blood or, failing that, stored within extracellular drusen for later processing [175,176,177]

Consistently, the elevated serum acylcarnitine levels in our MMA cohort, particularly in patients with MUT mutations, may reflect a combination of treatment-related acylcarnitine export and underlying disturbances in fatty acid oxidation and mitochondrial homeostasis

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Individual results vary based on age, health status, lifestyle factors, and treatment adherence

Endocrine , 14(3), 307314

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