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Skin renewal activity of non-thermal plasma through the activation of beta-catenin in keratinocytes

NIH/3T3 cells (5 10 cells per well) were seeded onto the hydrogel surface and incubated for 24 h

The two interact in different parts of the collagen pathway Vitamin C as an enzymatic cofactor, GHK-Cu as a signaling input

Follow this same process on other areas around the face, neck, decolletage and hands to target your concerns

Nat Rev Immunol (2020) 20(1):724

The copper content of GHK-Cu formulations has been a theoretical safety consideration, given that excessive copper can be toxic - however, the amounts used in cosmetic and research applications are extremely small, the copper is tightly chelated by the peptide (reducing free copper availability), and topical absorption of copper from these products appears minimal and well below levels that would cause systemic copper accumulation or toxicity