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GLP-1 agonists might protect the heart indirectly through their effects on weight, blood sugar, blood pressure, and inflammation

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Why the Combination Matters The three-receptor activity creates what researchers describe as a complementary pharmacological triangle: GLP-1 reduces intake, GIP enhances the metabolic benefits of incretin signaling, and glucagon increases energy output

Potential use of exenatide for the treatment of obesity

GLP-1=glucagon-like peptide-1