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A 35-year-old CrossFit competitor in Vancouver underwent rotator cuff repair surgery four weeks ago

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Human StudiesWhat We Know Heres the catch: all of the research mentioned above has been done in animal models

Free Radical Biol Med 200:5972 Liubas N, Iskra R, Lubenets V (2023) Antioxidant defense system of rat liver under the influence of thiosulfonate esters

Under inflammatory conditions, pro-inflammatory cytokines [e.g., interferon-gamma (IFN-)] can activate IDO1, diverting Trp metabolism toward the kynurenine (KYN) pathway while inhibiting 5-HT synthesis, resulting in serotonin depletion and exacerbation of neurotransmitter imbalance (Rus et al., 2015)