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[7] [9] Patients with hemochromatosis or other iron overload disorders should not receive large doses of ascorbic acid, as it can enhance iron absorption and exacerbate tissue deposition

Results from trials of acarbose, metformin and rosiglitazone in prediabetic populations are summarised in Table 1

Cell-free in vitro methods offer precision, high throughput and control to identify the direct interaction of a compound or extract with a specific molecular target (e.g., enzymes, receptors), being suitable for initial screening (59, 60)

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