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In contrast, resmetirom targets hepatic THR- directly, improving intrahepatic lipid handling and fibrogenesis, with minor effects on systemic weight [Figure 1C]

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Consistent with previous findings 101 , adult-type ISC II cells were enriched in the G1 phase of the cell cycle, and similarly, LGR5 high fetal-type ISC I cells were mainly in the G1 phase (Supplementary Fig

Diarrhea: Chronic diarrhea can result in significant fluid and electrolyte losses, further exacerbating dehydration

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