Following T cell receptor (TCR) activation, zinc ions enter the cell via zinc transporters such as Zip6 and Zip8, facilitating the signaling pathways necessary for T cell activation and proliferation [69, 304]
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443 Furthermore, systemic AAV vector-mediated LAV-BPIFB4 gene transfer has been shown to redirect circulating SnCs to the spleen and increase the activity of immune cells within the spleen, thereby effectively eliminating senescent immune cells
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By fitting principal graph within each partition, trajectory graph was constructed
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