Fatty acid/lipid metabolism in IR The specific insulin actions in adipose tissue include activation of glucose uptake and triglyceride synthesis, suppression of triglyceride hydrolysis and free fatty acids (FFA) and glycerol release into the blood circulation
A recent study from the University of Copenhagen raises new concerns about GLP-1 medications, including Ozempic, Wegovy, and Mounjaro, highlighting potential bone density loss
Although a zinc chloride-based formulation of taspoglutide, facilitating subcutaneous precipitation, showed promising results, phase 3 trials were completed, but a submission for approval was discontinued, due to a number of cases of anaphylactic shock (49, 50)
It has become standard for peptides to be injected subcutaneously, given both the predictability of absorption and evasion of gut breakdown
He has worked as a clinical dietitian, founded and grown a large private practice, is author of The Tweaking Diet, and has developed MEALZEE, a meal-planning app used by health professionals across Australia and New Zealand
Genet 15 , 48 (2014)