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Cytochrome P450 enzymes involved in acetaminophen activation by rat and human liver micro-somes and their kinetics

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Erythrocytes were lysed twice by adding DEPC-treated H 2 O and NaCl (8.8%), followed by centrifugation (450 x g, 6 min, 4C, Universal 320 R, Hettich, Tuttlingen, Germany)

If subcutaneous injection is completely off the table for you, oral products become the obvious choice by default