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Lentivirus production The following plasmids were used for lentivirus production: psPAX2 packaging plasmid (Addgene, #12260), pMD2-G VSV-G envelope plasmid (Addgene, #12259), Blast-Cas9 plasmid, pKLV2-U6gRNA5(gGFP)-PGKBFP2AGFP-W reporter plasmid (Addgene, #67980), and custom pooled CRISPR libraries

Grogginess: Morning grogginess suggests either excessive dosing or poor timing

Both DRD1 and DRD2 are expressed in the LHb (Proulx et al., 2014)