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Extracellular Matrix Studies The extracellular matrix is far more than a structural scaffold: it actively influences cell behavior, signaling, and tissue organization

Funding This paper was supported by San Matteo Hospital Foundation, Internal Medicine research fundings, PRIN2017. Publishers note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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To enhance the oral absorbtion of the drug, metformin prodrugs were developed with improved permeability across the lipid membrane 120