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In January 2025, Novo Nordisk disclosed key findings from the STEP UP study , a Phase IIIb trial within the global STEP program

Research published in metabolic and nephrology journals indicates that patients with NAFLD have a higher prevalence of kidney stones compared to those without liver disease, and conversely, individuals with recurrent kidney stones show increased rates of fatty liver

Once you discontinue treatment, your natural hunger signals gradually reactivate, typically over 2 to 4 weeks, though the timeline varies by individual metabolism and how long you used the medication

Clinically, this phase is used to reassess how the body is responding to ongoing appetite suppression

Gently swirl (never shake) until dissolved

But before endorsing off-label strategies like slicing pens or stretching prescriptions, its essential to individualize care