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The cardiovascular benefits observed were associated with improved glycemic control and weight loss, though the precise mechanisms contributing to MACE reduction remain under investigation

What is established across the class is that when the drug stops, hunger returns, metabolic rate may decline, insulin sensitivity may worsen and fat oxidation drops

The nerve gets hurt, it gets inflamed, the inflammation hurts the nerve more, and the cycle repeats

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Kwaifa IK, Mainasara AS, Jidda ML, Amin AM, Abdullahi G, Ladan F, Danyaro M (2023) Non-alcoholic fatty liver disease: pathogenesis and the significance of high-density lipoprotein as a molecular modifier