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Purpose-built for physicians 5:2 intermittent fasting plus meal replacement improves glycemic control, weight loss Key takeaways: On average, patients assigned to the diet lost 9.7 kg and reduced their HbA1c by 1.9%

Patients should not expect immediate changes in erectile function upon starting the medication

doi: 10.1001/jama.297.8.842

Also, adherence and treatment satisfaction may increase in a regimen that does not increase the daily number of injections, while still promoting weight neutrality or loss and reduced frequencies of hypoglycemic episodes

According to the authors, this difference may occur because some cells internalize or break down their GLP-1 receptors, reducing the drugs ability to continue signaling

Can insulin resistance make semaglutide weight loss slower