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Moreover, nigella sativa decreases hepatitis viral load, improves response to oxidative stress and improves the clinical condition and glycemic control in hepatitis patients (Box 3)
Primary hepatic models Although the study of drugs metabolism in the gut is evolving, it is still falling behind the established liver models to some extent
Effects on vulnerable populations (pregnant women, children, immunocompromised individuals) are unknown
Studies investigating the regulation of ion channels relevant to mitochondrial iron transport and cardiac dysfunction due to iron overload have demonstrated that the MCU facilitates the transport of Fe2 + into the mitochondria, while Mfrn2 may serve a regulatory function in this process [11]
TMT liquid chromatography-mass-spectrometry (LC-MS) analysis Samples were analyzed by liquid chromatography-tandem mass spectrometry using an Orbitrap Fusion Tribrid Mass Spectrometer (Thermo Scientific) coupled to an UltiMate 3000 Series Rapid Separation LC system and autosampler (Thermo Scientific Dionex)
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