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Metabolism 31 , 784790 (1982)

Harnett JE, Pyne DB, McKune AJ, Penm J, Pumpa KL

Compared with conventional GLP-1 receptor agonists, such as liraglutide and semaglutide, tirzepatide has demonstrated superior efficacy in body weight control in several phase III clinical trials, with average weight reductions exceeding 20% in some study populations (15)

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Some people notice better sleep quality and morning energy as their growth hormone rhythm improves, even before they see a visible change at the waist