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10.1016/j.cardiores.2006.01.022 278 TerpstraM.TorkelsonC.EmirU.HodgesJ

Key Takeaway: While the core molecule (semaglutide) is chemically identical in both compounded and branded versions, the final preparationincluding inactive ingredients and how the medication is packagedis what differentiates them

Everett BM

It includes 25P/28P/29P mutations to reduce the proteins propensity to form fibrils and -sheets and the insertion of a C-terminal proline improves binding to the CTR channel