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Their vesicular structure enables encapsulation of both hydrophilic and lipophilic drugs, with enhanced dermal penetration and sustained drug release [136]
Once-weekly exenatide versus once- or twice-daily insulin detemir: randomized, open-label, clinical trial of efficacy and safety in patients with type 2 diabetes treated with metformin alone or in combination with sulfonylureas
Another study utilizing FISH and multiple ligation-dependent probe amplification (MLPA) for the 9p21 deletion also found alterations at 9p21 occurred more frequently in Spitz tumors versus Spitz nevi [52]
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