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We knew weight loss treatments such as bariatric surgery and lifestyle interventions improve cancer survival, and results of the growing number of evidence-based studies looking at GLP-1s among people with cancer made us think we would see a mortality reduction, Tatum said

The accelerated approval requires confirmatory evidence from the ESSENCE trial and other ongoing studies to validate long-term clinical benefit.

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Heres what the team at Southdowns commonly sees: Noticing several of these together is a signal worth acting on

Over time, it causes fewer dark spots, melasma, and hyperpigmentation, resulting in a lighter, more even-looking skin tone

These structural features strengthen resistance to DPP-4 degradation and support extended stability in controlled research environments