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It is intended to be used in conjunction with a reduced calorie diet and increased physical activity for adults with obesity or who are overweight and also have weight-related medical problems

Clinical trial found semaglutide reduced liver inflammation and scarring Nearly two in three people with fatty liver disease lost some of the liver fat and inflammation after using semaglutide 2.4 mg weekly shots for one-and-a-half years, according to initial results from an ongoing phase 3 trial, published recently in the New England Journal of Medicine

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Among the other markers of atherosclerosis, BNP, which is secreted mainly by the ventricular myocardium 53,54,55 , has been found to decrease significantly by the GLP-1-based therapies but MCP-1, which is secreted by the peripheral blood mononuclear cells 56 , has been found un-affected by the GLP-1-based therapies, in the present study

Slow down: behavioural and physiological effects of reducing eating rate

However, the cardioprotective effects of GLP-1 RAs may be explained beyond traditional risk factors modification