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doi:10.1186/s13023-022-02179-y

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Weight loss with naltrexone SR/bupropion SR combination therapy as an adjunct to behavior modification the COR-BMOD trial

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The safest interpretation is that 5-Amino-1MQ is an early-stage research compound with possible metabolic relevance, not a proven replacement for medical treatment, nutrition, exercise, sleep, or provider-guided weight-loss care

The pairing mimics the body's natural two-signal GH regulation system