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"Our study will have a major impact on clinical guidelines for the management of chronic kidney disease and cardiovascular disease in people with and without diabetes," said study co-author Dr

doi: 10.3389/fmolb.2022.925700 Received 21 April 2022 Accepted 29 June 2022 Published 22 July 2022 Volume 9 - 2022 Edited by Yan Chen, Second Xiangya Hospital, Central South University, China Reviewed by Jungang Xie, Huazhong University of Science and Technology, China Zhiyi He, Guangxi Medical University, China Updates Copyright 2022 Zhang, Yan, Lu and Zhou

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By contrast, short-chain fatty acids (SCFAs), particularly butyrate, exert protective effects by engaging GPR41/43 and inhibiting histone deacetylases, thereby reinforcing epithelial barrier integrity and suppressing NF-B/TGF- pathways (49)

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doi: 10.2527/2001.79123104x