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Study-related adverse events In a 26-week, open-label study in adult patients (N=665) comparing Victoza 1.2 mg, Victoza 1.8 mg, and sitagliptin 100 mg, all in combination with metformin, the adverse reactions reported in 5% of patients treated with Victoza were nausea (23.9% vs 4.6%), headache (10.3% vs 10.0%), diarrhea (9.3% vs 4.6%), and vomiting (8.7% vs 4.1%)

Do not use appetite suppression as an excuse to eat a low-fat diet

Using AOD-9604 without dietary modification is unlikely to produce noticeable before-and-after changes

The vertical axis shows years and the horizontal axis shows numbers of patients

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Interestingly, recent evidences indicate that GLP1R agonists can significantly reduce adverse cardiovascular events, renal dysfunction, and the incidence of stroke in the patients with diabetes 9,10,11,12