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TB-500 interacts with G-actin through the conserved LKKTET motif, influencing actin polymerization dynamics, cytoskeletal organization, and actin-associated signaling pathways

The p53 signaling pathway, TNF-mediated signaling pathways, cytokine-cytokine receptor interaction, and helper T-cell immune response signaling pathways are associated with high-risk FRlncRNAs (116)

There is a significant interaction between cognitive-psychiatric symptoms and UA in female patients, which may explain the heterogeneous findings that did not consider differences between males and females [108]