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J Clin Invest 112:18311842 Zhang CY, Baffy G, Perret P et al (2001) Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes

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During B1 and marginal zone B cell development, maintenance, and immunity, GPX4 is necessary to promote ferroptosis

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16 Matthias Tschp and his team discovered that dual agonists targeting both GLP-1 and GIP receptors (GIPR) are more effective in treating diabetes than those targeting only GLP-1R